Abstract: The JKN-3×2.2P winding mine hoist as the research object, in view of the fact that the spindle device of the hoist sustains the dynamic load from the outer rotor drum in the actual operation condition, the problem that the spindle device of the whole hoisting system cannot avoid vibration is studied. Based on SolidWorks platform, the three-dimensional model of the key bearing parts of the hoist spindle device is built, and it is coupled to ANSYS Workbench platform to complete the finite element model construction. Through numerical simulation, the modal and harmonic response of the hoist spindle device is analyzed, and the amplitude-frequency response of the whole structure of the hoist spindle device under different frequency ranges is determined. Finally, the vibration characteristics test of the hoist spindle device is completed. The research shows that the sensitive frequency range of the hoist spindle device is around 14~83 Hz, and its vibration signal fluctuates greatly in the acceleration and deceleration operation stage, and the vibration signal is relatively stable in the uniform speed stage. The research results provide a theoretical basis for the safe and efficient operation of mine hoist.