Abstract: A plate replacement structure for printing roller has been designed, with improvements made in terms of bearing, repeatable positioning accuracy, and operational convenience. Traditional methods rely on push-pulling flipping seat, locking for manual, and using planar positioning, resulting in long plate changing times and large positioning errors. For the replacement structure of the printing plate, a bearing with stronger load capacity has been selected. It adopts cylinder drive combined with taper positioning technology, and achieves automatic separation and resetting of the core shaft and push-pull base through reciprocating motion of the cylinder. The high-precision repeatable positioning is ensured by the conical surface fit between the cone top and the cone sleeve. After optimizing the design of the plate changing structure, compared with the traditional structure, it has higher positioning accuracy and efficiency, which can save manpower while improving printing quality.