Abstract: In response to the existing shortcomings of data communication lag, low automation and intelligence level in the monitoring and control system of mine substations, a substation automation monitoring system was designed based on the main requirements of the mining substation monitoring system. The main structure of the system was designed, and its main monitoring logic and functions were analyzed. The new system clustered the measurement and control devices and centralized the measurement and control functions of the intervals in the substation. Through practical application testing, it was found that deleting the new monitoring system can improve the data communication efficiency in the substation by 88.3%, reduce the operation failure rate of the substation by 87.5%, and achieve good monitoring effect. This design can provide reference for the optimization design of the monitoring system of mine substations under similar working conditions.